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Performance analysis of novel toxin-antidote CRISPR gene drive systems

2019-05-05

Abstract excerpt

<h4>ABSTRACT</h4> Gene drives can potentially fixate in a population by biasing inheritance in their favor, opening up a variety of potential applications in areas such as disease-vector control and conservation. CRISPR homing gene drives have shown much promise for providing an effective drive mechanism, but they typically suffer from the rapid formation of resistance alleles. Even if the problem of resistance c...

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Literature Corpus work
0725c5b8-2bad-5680-8846-5684c1c3e868
DOI
10.1101/628362
Open publication

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