Article

Initial efficacy determination and resistance profile of anti- <i>Acinetobacter</i> antibiotics, turnercyclamycins

2021-11-03

Abstract excerpt

Drug-resistant Acinetobacter is a challenging, deadly pathogen of increasing prevalence in the US healthcare system. Recently, we described a series of lipopeptides, the turnercyclamycins, which retain potency against Acinetobacter strains that are resistant to the last-line antibiotic, colistin. To further evaluate the potential of turnercyclamycins, we completed mouse efficacy, pharmacokinetics, and toxicity s...

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Literature Corpus work: 75a58490-8eb3-5904-8a74-b658eabd7288
DOI: 10.1101/2021.11.01.466777

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