Back to search

Article

The commercial antimicrobial triclosan induces high levels of antibiotic tolerance <i>in vitro</i> and reduces antibiotic efficacy up to 100-fold <i>in vivo</i>

2016-12-01

Abstract excerpt

The antimicrobial triclosan is used in a wide range of consumer products ranging from toothpaste, cleansers, socks, and baby toys. A bacteriostatic inhibitor of fatty acid synthesis, triclosan is extremely stable and accumulates in the environment. Approximately 75% of adults in the US have detectable levels of the compound in their urine, with a sizeable fraction of individuals (>10%) having urine concentrations...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d0435320-c978-56e2-97ba-0f1ad933ba0f
DOI
10.1101/090829
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The commercial antimicrobial triclosan induces high levels of antibiotic tolerance <i>in vitro</i> and reduces antibiotic efficacy up to 100-fold <i>in vivo</i>DOI 10.1101/090829
Silver nanoparticles induce a <i>triclosan-like</i> antibacterial action mechanism in multi-drug resistant <i>Klebsiella pneumoniae</i>Semantic proximity
Off-purpose activity of industrial and agricultural chemicals against human gut bacteriaSemantic proximity
Genomic fitness profiling of Acinetobacter baumannii reveals modes of action for common biocides and mechanisms of biocide-antibiotic antagonismSemantic proximity
Antibiotic Resistance in <i>Bacillus</i> -based Biopesticide ProductsSemantic proximity
Diclofenac sensitizes multi-drug resistant <i>Acinetobacter baumannii</i> to colistinSemantic proximity
Understanding tolerance to cell wall–active antibioticsSemantic proximity
TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance.Semantic proximity
Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureusSemantic proximity
Purine and pyrimidine analogues differentially regulate cell wall precursor biosynthesis to control β-lactam susceptibility in methicillin resistant <i>Staphylococcus aureus</i>Semantic proximity
<i>Staphylococcus aureus</i> TargetArray: Comprehensive Differential Essential Gene Expression as a Mechanistic Tool To Profile AntibacterialsSemantic proximity
Uncovering the mechanisms of clinically-relevant altered antibiotic responses of <i>Staphylococcus aureus</i> under wound infection-mimetic conditionsSemantic proximity
Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure.Semantic proximity
Select a neighboring publication to make it the new centre.