Article

The complexity and dynamics of <i>in organello</i> translation assessed by high-resolution mitochondrial ribosome profiling

2023-07-20

Abstract excerpt

Since mitochondrial translation serves the essential subunits of the OXPHOS complex that produces ATP, exhaustive, quantitative, and high-resolution delineation of mitoribosome traversal is needed. Here, we developed a technique for high-resolution mitochondrial ribosome profiling and revealed the intricate regulation of mammals in organello translation. Our approach assessed the stoichiometry and kinetics of mit...

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Identifiers and source

Literature Corpus work: 759ed2a2-ec39-5ae9-96e6-2718c1ee5473
DOI: 10.1101/2023.07.19.549812

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