Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Mitoribosome Biogenesis and Its Emerging Links to Disease.

International journal of molecular sciences - 7 Apr 2021

Lopez Sanchez Maria Isabel G, Krüger Annika, Shiriaev Dmitrii I, Liu Yong, Rorbach Joanna

Abstract excerpt

Mammalian mitochondrial ribosomes (mitoribosomes) synthesize a small subset of proteins, which are essential components of the oxidative phosphorylation machinery. Therefore, their function is of fundamental importance to cellular metabolism. The assembly of mitoribosomes is a complex process that progresses through numerous maturation and protein-binding events coordinated by the actions of several assembly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Disease Susceptibility
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondria

Share to Mitochondrial Proteins

Share to Oxidative Phosphorylation

Share to Protein Processing, Post-Translational

Share to Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33917098
DOI: 10.3390/ijms22083827
PMCID: PMC8067846

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Mitoribosome Biogenesis and Its Emerging Links to Disease.PMID 33917098Read ↗

The Diseased Mitoribosome.Semantic proximity Read ↗

GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translationSemantic proximity Read ↗

An Update on Mitochondrial Ribosome Biology: The Plant Mitoribosome in the Spotlight.Semantic proximity Read ↗

Blackout in the powerhouse: clinical phenotypes associated with defects in the assembly of OXPHOS complexes and the mitoribosome.Semantic proximity Read ↗

Structural insights into unique features of the human mitochondrial ribosome recyclingSemantic proximity Read ↗

Modular maturation and novel assembly factors in the biogenesis of human mitochondrial small ribosomal subunitSemantic proximity Read ↗

BOLA3 and NFU1 link mitoribosome iron-sulfur cluster assembly to multiple mitochondrial dysfunctions syndromeSemantic proximity Read ↗

Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease.Semantic proximity Read ↗

Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune ReactionSemantic proximity Read ↗

Molecular mechanism of mitochondrial respiratory chain assembly and its relation to mitochondrial diseases.Semantic proximity Read ↗

Molecular Insights into Mitochondrial Protein Translocation and Human Disease.Semantic proximity Read ↗

Identification and Validation of Toxoplasma gondii Mitoribosomal Large Subunit ComponentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.