Article

Epistasis analysis reveals associations between gene variants and bipolar disorder

2017-09-11

Abstract excerpt

In complex phenotypes (e.g., psychiatric diseases) single locus tests, commonly performed with Genome-Wide Association Studies, have proven to be limited in discovering strong gene associations. A growing body of evidence suggests that epistatic non-linear effects may be responsible for complex phenotypes arising from the interaction of different biological factors. A major issue in epistasis analysis is the compu...

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Literature Corpus work: 7581b211-360b-5d65-aaf2-e72a6c6a56ff
DOI: 10.7287/peerj.preprints.3242v1

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