Article

Data-Driven Mechanistic Computational Modeling of Human Cell Cycle Phases for Defining Inhibitor Combinations in Silico

2026-02-06

Abstract excerpt

<h4>ABSTRACT</h4> The human cell cycle is a highly regulated process that integrates multiple signaling pathways and checkpoints to ensure faithful genome duplication and cell division. Disruptions in these regulatory networks contribute to a wide range of diseases. Here, we present a novel, updateable computational model of the full human cell cycle that shows sustained oscillations over time and reproduces expe...

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Literature Corpus work: 7578911c-82dd-57e8-92e0-79afb878471e
DOI: 10.64898/2026.02.04.703693

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