Article

Reusable rule-based cell cycle model explains compartment-resolved dynamics of 16 observables in RPE-1 cells

2023-05-05

Abstract excerpt

The mammalian cell cycle is regulated by a well-studied but complex biochemical reaction system. Computational models provide a particularly systematic and systemic description of the mechanisms governing mammalian cell cycle control. By combining both state-of-the-art multiplexed experimental methods and powerful computational tools, this work aims at improving on these models along four dimensions: model structu...

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Literature Corpus work: cf09daff-942b-5c12-9836-793e6535c5b9
DOI: 10.1101/2023.05.04.539349

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