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Article

The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer.

Cell proliferation - 1 Jun 2003

Vermeulen Katrien, Van Bockstaele Dirk R, Berneman Zwi N

Abstract excerpt

The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This review will focus on these mechanisms, i.e. regulation of cyclin-dependent kinases (CDK) by cyclins, CDK inhibitors and phosphorylating events. The quality checkpoints activated after DNA damage are also discussed. The complexity of the regulation of the cell cycle is also reflected in the different alterations leading to...

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Identifiers

PMID: 12814430
DOI: 10.1046/j.1365-2184.2003.00266.x
PMCID: PMC6496723

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UCN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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