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Correction of Preeclampsia by Intraplacental Gene Transfer of IGF-1 in the BPH/5 Mouse via NF-KB Mediated Induction of Angiogenic Gene Expression

2026-01-16

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction.</bold> Preeclampsia causes severe complications for the mother, fetus, and newborn, yet the underlying mechanisms remain poorly understood. The BPH/5 mouse is the only spontaneous mouse model that recapitulates key features of human preeclampsia. Although impaired angiogenesis and endothelial dysfunction are hallmarks of this disease, the molecular pathways capabl...

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Literature Corpus work
75579acc-0cad-5632-b363-31abc006bcbf
DOI
10.21203/rs.3.rs-8563004/v1
Open publication

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Correction of Preeclampsia by Intraplacental Gene Transfer of IGF-1 in the BPH/5 Mouse via NF-KB Mediated Induction of Angiogenic Gene ExpressionDOI 10.21203/rs.3.rs-8563004/v1
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