Article

Parallel Factor ChIP Provides Essential Internal Control for Quantitative Differential ChIP-Seq

2017-08-30

Abstract excerpt

<h4>ABSTRACT</h4> A key challenge in quantitative ChIP-seq is the normalisation of data in the presence of genome-wide changes in occupancy. Analysis-based normalisation methods were developed for transcriptomic data and these are dependent on the underlying assumption that total transcription does not change between conditions. For genome-wide changes in transcription factor binding, these assumptions do not hol...

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Literature Corpus work: 7555bea9-27d8-57ab-8268-88efffff01af
DOI: 10.1101/182261

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