Article

Beyond library size: a field guide to NGS normalization

2014-06-19

Abstract excerpt

<h4>Background:</h4> Next generation sequencing (NGS) is a widely used technology in both basic research and clinical settings and it will continue to have a major impact on biomedical sciences. However, the use of incorrect normalization methods can lead to systematic biases and spurious results, making the selection of an appropriate normalization strategy a crucial and often overlooked part of NGS analysis. <h...

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Literature Corpus work: f7ef7acc-6664-5fe2-ae8e-4fc0307fe931
DOI: 10.1101/006403

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