Article

Host adaptation and convergent evolution increases antibiotic resistance without loss of virulence in a major human pathogen

2018-07-17

Abstract excerpt

As human population density and antibiotic exposure increases, specialised bacterial subtypes have begun to emerge. Arising among species that are common commensals and infrequent pathogens, antibiotic-resistant ‘high-risk clones’ have evolved to better survive in the modern human. Here, we show that the major matrix porin (OmpK35) of Klebsiella pneumoniae is not required in the mammalian host for colonisation, p...

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Literature Corpus work: 754232e8-7fbc-54eb-b064-d93fd260ff6b
DOI: 10.1101/370940

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