Article

<i>Klebsiella pneumoniae</i> OmpR facilitates lung infection through transcriptional regulation of key virulence factors

2023-07-31

Abstract excerpt

Bacteria must adapt to the stresses of specific environmental conditions to survive. This adaptation is often achieved by altering gene expression through two-component regulatory systems (TCSs). In Gram-negative bacteria, the response to environmental changes in osmolarity and pH are primarily mediated by the EnvZ/OmpR TCS. Although the functioning of EnvZ/OmpR has been well characterized in Escherichia coli ,...

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Literature Corpus work: 6bddc56f-83ea-5c7d-b98f-653b47c0963a
DOI: 10.1101/2023.07.31.550992

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