Article

Holistic in silico developability assessment of novel classes of small proteins using publicly available sequence-based predictors

2023-11-11

Abstract excerpt

The development of novel therapeutic proteins is a lengthy and costly process, with an average attrition rate of 91% (Thomas et al., 2021). To increase the probability of success and ensure robust drug supply beyond approval, it is essential to assess the developability profile of new potential drug candidates as early and broadly as possible in development (Jain et al., 2023). Predicting these properties in sili...

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Literature Corpus work: 7539fb6a-d94d-590c-b73b-32af27addd25
DOI: 10.1101/2023.11.10.566515

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