Article

Predicting and Interpreting Protein Developability via Transfer of Convolutional Sequence Representation

2022-11-25

Abstract excerpt

Engineered proteins have emerged as novel diagnostics, therapeutics, and catalysts. Often, poor protein developability – quantified by expression, solubility, and stability – hinders utility. The ability to predict protein developability from amino acid sequence would reduce the experimental burden when selecting candidates. Recent advances in screening technologies enabled a high-throughput developability dataset...

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Literature Corpus work: 3c2c4561-762a-5f0c-88b4-9f36ff7b6a8a
DOI: 10.1101/2022.11.21.517400

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