Article

Identifying Protein Features Responsible for Improved Drug Repurposing Accuracies Using The CANDO Platform: Implications for Drug Design

2018-11-19

Abstract excerpt

Drug repurposing is a valuable tool for combating the slowing rates of novel therapeutic discovery. The Computational Analysis of Novel Drug Opportunities (CANDO) platform performs shotgun repurposing of 2030 indications/diseases using 3733 drugs/compounds to predict interactions with 46,784 proteins and relating them via proteomic interaction signatures. An accuracy is calculated by comparing interaction similari...

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Literature Corpus work: f8d90b9e-d27d-529f-a0d0-84487e192a66
DOI: 10.20944/preprints201811.0429.v1

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