Article

Tackling the role of rare functional variation in inflammatory bowel disease through application of GenePy2 as a potential DNA biomarker

2024-05-23

Abstract excerpt

<title>Abstract</title> <p>Rare and common variants often converge in the pathogenic pathway of in inflammatory bowel disease (IBD), a heterogenous autoimmune condition with genomic and environmental influences. We identified 794 functionally-targeted-genes/linkage-disequilibrium-mapped blocks (LDBs) implicated by genome-wide-association-studies (GWAS), then developed GenePy2, a burden score that integrates funct...

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Literature Corpus work: 7526fba6-3b2b-53f1-a1ef-be88e48109c2
DOI: 10.21203/rs.3.rs-4415057/v1

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