Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort

28 Mar 2018

Abstract excerpt

In the United States, approximately 5% of individuals with inflammatory bowel disease (IBD) are younger than 20 years old. Studies of pediatric cohorts can provide unique insights into genetic architecture of IBD, which includes Crohn's disease (CD) and ulcerative colitis (UC). Large genome-wide association studies have found more than 200 IBD-associated loci but explain a minority of disease variance for CD and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Helicobacter pylori-related gastroenterology studies
Share to IL-33, ST2, and ILC Pathways
Share to Inflammatory Bowel Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29593342
DOI: 10.1038/s41435-018-0015-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohortPMID 29593342Read ↗

Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes.Semantic proximity Read ↗

Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population.Semantic proximity Read ↗

Pediatric inflammatory bowel disease: clinical and molecular genetics.Semantic proximity Read ↗

Rare and common variant discovery in complex disease: the IBD case studySemantic proximity Read ↗

Exome Analysis of Rare and Common Variants within the NOD Signaling Pathway.Semantic proximity Read ↗

The role of monogenic disease in children with very early onset inflammatory bowel disease.Semantic proximity Read ↗

Genetic Sequencing of Pediatric Patients Identifies Mutations in Monogenic Inflammatory Bowel Disease Genes that Translate to Distinct Clinical Phenotypes.Semantic proximity Read ↗

Role of genetics in pediatric inflammatory bowel disease.Semantic proximity Read ↗

Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated With Monogenic Variants, Identified by Whole-Exome Sequencing in 1000 Children at a Single Center.Semantic proximity Read ↗

The genetic background of inflammatory bowel disease: from correlation to causality.Semantic proximity Read ↗

Exome sequencing directly implicates 68 genes in inflammatory bowel diseaseSemantic proximity Read ↗

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at <i>ADCY7</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.