Article

CETP Expression in Bone Marrow Derived Cells Reduces Inflammatory Features of Atherosclerosis in Hypercholesterolemic Mice

2023-07-27

Abstract excerpt

CETP activity reduces plasma HDL-cholesterol concentrations, a correlate of increased risk of atherosclerotic events. However, our recent findings suggest that CETP expression in macrophages promotes an intracellular antioxidant state, reduces free cholesterol accumulation and phagocytosis, and attenuates pro-inflammatory gene expression. To determine whether CETP expression in macrophages affects atherosclerosis...

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Literature Corpus work: 74d8f226-9891-5e19-a5fe-c02d1a79a133
DOI: 10.20944/preprints202307.1930.v1

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