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Article

Plasma high density lipoproteins: Therapeutic targeting and links to atherogenic inflammation.

Atherosclerosis - 1 Sept 2018

Tall Alan R

Abstract excerpt

Plasma HDL levels have an inverse relationship to coronary artery disease (CAD) risk, which led to the idea that increasing HDL levels therapeutically would ameliorate atherosclerosis. Human genetic deficiency of CETP caused markedly elevated HDL and moderately reduced non-HDL cholesterol levels, suggesting that CETP inhibitors might produce cardiovascular benefit. The CETP inhibitor anacetrapib reproduced the...

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Share to Anti-Inflammatory Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol Ester Transfer Proteins

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Share to Inflammasomes

Share to Lipoproteins, HDL

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Source

Identifiers

PMID: 30029099
DOI: 10.1016/j.atherosclerosis.2018.07.004

Genes

CAD
CETP
ABCA1
ABCG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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