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Article

Macrophages and T cells in atherosclerosis: a translational perspective

14 Jun 2019

Abstract excerpt

Atherosclerosis is now considered a chronic maladaptive inflammatory disease. The hallmark feature in both human and murine disease is atherosclerotic plaques. Macrophages and various T-cell lineages play a crucial role in atherosclerotic plaque establishment and disease progression. Humans and mice share many of the same processes that occur within atherogenesis. The various similarities enable considerable...

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PMID: 31199186
DOI: 10.1152/ajpheart.00206.2019

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