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Busulfan pharmacokinetics in adults – a real-world evaluation of intra-individual variabil-ity and the impact of obesity and deferasirox

2025-10-06

Abstract excerpt

<title>Abstract</title> <p> To avoid under- or overexposure caused by a high variability of busulfan’s pharmacokinetic parameters, therapeutic drug monitoring (TDM) is highly recommended. Nevertheless, it is not widely used in European transplant centers. We retrospectively analyzed real-world busulfan TDM data in adults in our center between 9/2016 and 11/2024 with special focus on overweight/obesity and comedi...

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Literature Corpus work
74c5a1d7-42ba-57dd-8884-b79b6ef6a6c9
DOI
10.21203/rs.3.rs-7660052/v1
Open publication

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Busulfan pharmacokinetics in adults – a real-world evaluation of intra-individual variabil-ity and the impact of obesity and deferasiroxDOI 10.21203/rs.3.rs-7660052/v1
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