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Systemic ELOVL6 activity predicts survival and represents a modifiable target of ALS

2026-05-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Amyotrophic lateral sclerosis (ALS) is characterized by profound metabolic reprogramming, yet the lack of biomarkers for specific druggable targets remains a major hurdle for precision medicine. We hypothesized that peripheral lipid biosynthetic signatures could serve as both prognostic indicators and a roadmap for identifying novel disease-modifying targets. <h4>Methods</h4...

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Literature Corpus work
744da1c4-302c-56ce-a880-21ed4b16517b
DOI
10.64898/2026.04.30.26352060
Open publication

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