Article

Mesenchymal stem cell-derived exosomal miR-27b-3p alleviates liver fibrosis via downregulating YAP/LOXL2 pathway

2023-03-06

Abstract excerpt

Lysyl oxidase-like 2 (LOXL2) is an extracellular copper-dependent enzyme that plays a central role in fibrosis by catalyzing the crosslinking and deposition of collagen. Therapeutic LOXL2 inhibition has been shown to suppress liver fibrosis progression and promote its reversal. This study aims to investigate the efficacy and underlying mechanisms of human umbilical cord-derived exosomes (MSC-ex) in LOXL2 inhibitio...

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Literature Corpus work: 74468302-e2c9-586a-afa9-d75d55b428b4
DOI: 10.21203/rs.3.rs-2637658/v1

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Mesenchymal stem cell-derived exosomal miR-27b-3p alleviates liver fibrosis via downregulating YAP/LOXL2 pathwayDOI 10.21203/rs.3.rs-2637658/v1Read

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