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3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway

2021-07-29

Abstract excerpt

<title>Abstract</title> <p>BackgroundExosomes secreted from stem cells exerted salutary effects on the fibrotic liver. Herein, the roles of exosomes derived from human embryonic stem cell (hESC) in anti-fibrosis were extensively investigated. Compared with two-dimensional (2D) culture, the clinical and biological relevance of three-dimensional (3D) cell spheroids were greater because of their higher regeneration...

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Literature Corpus work
90d44eb7-1500-57fa-bb5b-6ec87638f561
DOI
10.21203/rs.3.rs-736691/v1
Open publication

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3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathwayDOI 10.21203/rs.3.rs-736691/v1
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