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Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation

30 Apr 2020

Abstract excerpt

Articular cartilage remains among the most difficult tissues to regenerate due to its poor self-repair capacity. The lysyl oxidase family (LOX; also termed as protein-lysine 6-oxidase), mainly consists of lysyl oxidase (LO) and lysyl oxidase-like 1-4 (LOXL1-LOXL4), has been traditionally defined as cuproenzymes that are essential for stabilization of extracellular matrix, particularly cross-linking of collagen...

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PMID: 32426343
DOI: 10.3389/fbioe.2020.00359

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