Article

Recurrent Glioblastoma is Associated with a Closed DNA Conformation

2022-02-02

Abstract excerpt

<h4>Introduction: </h4> The pathological changes in epigenetics and gene regulation that accompany the progression of low-grade to high-grade gliomas are under-studied. The authors use a large set of paired atac-seq and RNA-seq data from surgically resected glioma specimens to infer gene regulatory relationships in glioma. <h4>Methods:</h4> Thirty-eight glioma patient samples underwent atac-seq sequencing and sixt...

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Literature Corpus work: 7442478d-7017-5991-bc9b-5de75194904d
DOI: 10.21203/rs.3.rs-922269/v2

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