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Article

Defining a Correlative Transcriptional Signature Associated with Bulk Histone H3 Acetylation Levels in Adult Glioblastomas

19 Jan 2023

Abstract excerpt

Glioblastoma (GB) is the most prevalent primary brain cancer and the most aggressive form of glioma because of its poor prognosis and high recurrence. To confirm the importance of epigenetics in glioma, we explored The Cancer Gene Atlas (TCGA) database and we found that several histone/DNA modifications and chromatin remodeling factors were affected at transcriptional and genetic levels in GB compared to...

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Epigenetics and DNA Methylation
Glioma Diagnosis and Treatment
Histone Deacetylase Inhibitors Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36766715
DOI: 10.3390/cells12030374

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