Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of germline PALB2 variants to an unselected and prospectively registered pancreatic cancer patient cohort in Pakistan.

HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 Dec 2022

Muhammad Noor, Sadaqat Rida, Naeemi Humaira, Masood Iqra, Hassan Usman, Ijaz Bushra, Hanif Faisal, Syed Aamir A, Yusuf Muhammed A, Rashid Muhammad U

Abstract excerpt

BACKGROUND: Partner and localizer of BRCA2 (PALB2) is a pancreatic cancer (PC) susceptibility gene reported in Caucasians. However, limited data are available among Asians. We investigated the contribution of PALB2 germline variants to Pakistani PC patients. METHODS: 150 unselected and prospectively enrolled PC patients were comprehensively screened for PALB2 variants, using denaturing high-performance liquid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Mutational Analysis
Share to Fanconi Anemia Complementation Group N Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Germ-Line Mutation

Share to Pancreatic Neoplasms

Source

Identifiers

PMID: 36175305
DOI: 10.1016/j.hpb.2022.09.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of germline PALB2 variants to an unselected and prospectively registered pancreatic cancer patient cohort in Pakistan.PMID 36175305Read ↗

Prevalence of PALB2 Germline Mutations in Early-onset and Familial Breast/Ovarian Cancer Patients from PakistanSemantic proximity Read ↗

Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy.Semantic proximity Read ↗

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families.Semantic proximity Read ↗

Analysis of PALB2 mutations in 155 Japanese patients with breast and/or ovarian cancer.Semantic proximity Read ↗

Management of individuals with germline variants in PALB2: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG).Semantic proximity Read ↗

PALB2 mutations in familial breast and pancreatic cancer.Semantic proximity Read ↗

PALB2 germline mutations in familial breast cancer cases with personal and family history of pancreatic cancerSemantic proximity Read ↗

Pathogenic CDKN2A germline variants are rare in a cohort of unselected pancreatic cancer patients from Pakistan.Semantic proximity Read ↗

Spectrum and characteristics of germline PALB2 pathogenic variants in 1556 early-onset breast cancer patients in China.Semantic proximity Read ↗

Genetic predisposition to pancreatic cancer.Semantic proximity Read ↗

PALB2 and the risks for cancer: implications for clinical care.Semantic proximity Read ↗

PALB2 mutations in breast cancer patients from a multi-ethnic region in northwest China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.