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Over-representation of MEF-2 isoforms (A/C) is associated with HTLV-1-induced acute ATLL and their recruitment to 3’LTR facilitates HBZ expression from the antisense promoter via interactions with Menin and Jun D

2021-04-03

Abstract excerpt

<title>Abstract</title> <bold>Background. </bold>HTLV-1 is a complex human retrovirus and an etiologic agent causing a malignant and intractable T-cell neoplasia termed Adult T-cell leukemia and lymphoma (ATLL). Patients suffering from ATLL present with poor prognoses and a dearth of treatment options warranting a continuous need to develop novel therapeutic targets. In contrast to the HTLV-1 transactivator pr...

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Literature Corpus work: 7421d529-afa4-5a01-8b75-61a86ae0026b
DOI: 10.21203/rs.3.rs-362537/v1

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Over-representation of MEF-2 isoforms (A/C) is associated with HTLV-1-induced acute ATLL and their recruitment to 3’LTR facilitates HBZ expression from the antisense promoter via interactions with Menin and Jun DDOI 10.21203/rs.3.rs-362537/v1Read

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