Article

The viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

2021-01-18

Abstract excerpt

<h4>SUMMARY</h4> While viral infections are known to hijack the transcription and translation of the host cell, the extent to which encoded viral proteins coordinate these perturbations remains unclear. Here we demonstrate that the oncoviral proteins Tax and HBZ interact with specific components of the spliceosome machinery, including the U2 auxiliary factor large subunit (U2AF2), and the complementary factor for...

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Literature Corpus work: f0a31050-cd42-55e9-abbe-f2b471dee6f0
DOI: 10.1101/2021.01.18.427104

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