Evaluation of ALKBH2 gene expression in patients with adult T-cell leukemia

Abstract excerpt

<h4>Background: </h4> Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus that causes adult T-cell leukemia (ATL). Patients infected with HTLV-1 are considered HTLV-1 carriers, and a small proportion of patients progress to life-threatening ATL after a long asymptomatic phase. Although countermeasures have been developed to combat HTLV-1 infection and ATL, their pathogenesis remains unclear. Recently...

Topics

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• Basic-Leucine Zipper Transcription Factors
• Gene Products, tax
• Human T-lymphotropic virus 1
• Leukemia-Lymphoma, Adult T-Cell
• NF-kappa B
• Receptors, TNF-Related Apoptosis-Inducing Ligand
• Retroviridae Proteins
• Viral Proteins

Identifiers and source

Literature Corpus work

74d4be53-5f98-579f-a11f-25a7de5a10dd

DOI

10.21203/rs.3.rs-3657256/v1