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Article

HTLV-1 subverts the innate immune effector gene IRF7 by viral HBZ protein for oncogenesis

2025-11-12

Abstract excerpt

<title>Abstract</title> <p>Interferon regulatory factors (IRFs) are innate immune transcription factors responsible for inducing the expression of type I interferons (IFN-I), which combat pathogen invasions via initiating the downstream Janus kinase signal transducer and activator of transcription (JAK-STAT) pathway. Among them, IRF7 plays a central role by forming heterodimers with IRF3 to initiate IFN-I product...

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Literature Corpus work
03479c43-e32f-5626-83f8-3fa31f74b50e
DOI
10.21203/rs.3.rs-7587883/v1
Open publication

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HTLV-1 subverts the innate immune effector gene IRF7 by viral HBZ protein for oncogenesisDOI 10.21203/rs.3.rs-7587883/v1
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