Article

MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expression

2024-03-18

Abstract excerpt

With our current appreciation of the complexity of eukaryotic transcription, whose dysregulation drives diseases including cancer, it is becoming apparent that identification of key events coordinating multiple aspects of transcriptional regulation is of special importance. To elucidate how assembly of RNA polymerase II (Pol II) with Mediator complex preinitiation complexes (PICs) and formation of transcription-pe...

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Literature Corpus work: 73fcc597-f27c-546e-a345-4d3f3edd5904
DOI: 10.1101/2024.03.18.585606

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MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expressionDOI 10.1101/2024.03.18.585606Read

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