Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The language of chromatin modification in human cancers.

Nature reviews. Cancer - 1 Jul 2021

Zhao Shuai, Allis C David, Wang Gang Greg

Abstract excerpt

The genetic information of human cells is stored in the context of chromatin, which is subjected to DNA methylation and various histone modifications. Such a 'language' of chromatin modification constitutes a fundamental means of gene and (epi)genome regulation, underlying a myriad of cellular and developmental processes. In recent years, mounting evidence has demonstrated that miswriting, misreading or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin
Share to DNA Methylation
Share to Histone Code

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

Share to Mutation

Share to Myeloid-Lymphoid Leukemia Protein

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 34002060
DOI: 10.1038/s41568-021-00357-x
PMCID: PMC10507815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The language of chromatin modification in human cancers.PMID 34002060Read ↗

Oncohistones: Exposing the nuances and vulnerabilities of epigenetic regulation.Semantic proximity Read ↗

Epigenetic changes in cancer.Semantic proximity Read ↗

Chromatin Mechanisms Driving Cancer.Semantic proximity Read ↗

Compendium of aberrant DNA methylation and histone modifications in cancer.Semantic proximity Read ↗

Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Cell and Tissue Structure, Function, and Phenotype.Semantic proximity Read ↗

Chromatin modifiers and carcinogenesis.Semantic proximity Read ↗

Chromatin modification and disease.Semantic proximity Read ↗

Epigenetics: Unravelling the cancer code.Semantic proximity Read ↗

Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.Semantic proximity Read ↗

Chromatin signatures of cancer.Semantic proximity Read ↗

Modifying chromatin and concepts of cancer.Semantic proximity Read ↗

The role of DNA methylation and histone modifications in transcriptional regulation in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.