Article

Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry

2021-06-03

Abstract excerpt

<h4>ABSTRACT</h4> The growing prevalence of opioid use disorder ( OUD ) constitutes an urgent health crisis. Ample evidence indicates that risk for OUD is heritable. As a surrogate (or proxy) for OUD, we explored the genetic basis of using prescription opioids ‘not as prescribed’. We hypothesized that misuse of opiates might be a heritable risk factor for OUD. To test this hypothesis, we performed a genome-wide as...

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Literature Corpus work: 73cf0d77-98bd-5c32-b7c0-4c6eddf18b95
DOI: 10.1101/2021.06.03.21258260

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