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Article

Genetic and non-genetic predictors of risk for opioid dependence.

Psychological medicine - 1 Jun 2024

Na Peter J, Deak Joseph D, Kranzler Henry R, Pietrzak Robert H, Gelernter Joel

Abstract excerpt

BACKGROUND: Elucidation of the interaction of biological and psychosocial/environmental factors on opioid dependence (OD) risk can inform our understanding of the etiology of OD. We examined the role of psychosocial/environmental factors in moderating polygenic risk for opioid use disorder (OUD). METHODS: Data from 1958 European ancestry adults who participated in the Yale-Penn 3 study were analyzed. Polygenic...

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Identifiers

PMID: 38317430
DOI: 10.1017/S0033291723003732
PMCID: PMC11132928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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