Article
Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry
1 Nov 2021
Abstract excerpt
Abstract The growing prevalence of opioid use disorder (OUD) constitutes an urgent health crisis. Ample evidence indicates that risk for OUD is heritable. As a surrogate (or proxy) for OUD, we explored the genetic basis of using prescription opioids ‘not as prescribed’. We hypothesized that misuse of opiates might be a heritable risk factor for OUD. To test this hypothesis, we performed a genome-wide association...
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