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HOXB6 and HOXB8 control immune-cancer cell interactions in pancreatic cancer

2024-09-06

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer lacking effective drugs and therefore new treatment targets are needed. Transcriptomic analysis comparing human embryonic and PDAC tissue identified a large overlap of expression profiles suggesting a re-initiation of developmental programs in pancreatic cancer. Specifically, we identified the transcription factors HOXB6 and HOXB8 as potential key regulato...

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Identifiers and source

Literature Corpus work
73a8a948-8559-54d1-a903-781d6df19c04
DOI
10.1101/2024.09.06.611619
Open publication

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HOXB6 and HOXB8 control immune-cancer cell interactions in pancreatic cancerDOI 10.1101/2024.09.06.611619
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