Article

A GATA6-centered gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

2020-04-09

Abstract excerpt

<h4>Objective</h4> Molecular taxonomy of tumors is the foundation of personalized medicine and is becoming of paramount importance for therapeutic purposes. Four transcriptomics-based classification systems of pancreatic ductal adenocarcinoma (PDAC) exist, which consistently identified a subtype of highly aggressive PDACs with basal-like features, including ΔNp63 expression and loss of the epithelial master regul...

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Literature Corpus work: 7a33f59c-3776-58ba-93ef-c63f14e4e59f
DOI: 10.1101/2020.04.09.033456

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