Article

Alpha-synuclein overexpression reduces neural activity within a basal ganglia vocal nucleus in a zebra finch model

2025-09-11

Abstract excerpt

Changes in vocal pitch, loudness, and timing are prevalent in Parkinson’s Disease (PD) and a target for early intervention and treatment. The neural mechanisms underlying these impairments are not understood, motivating work in animal models. The adult male zebra finch songbird is uniquely poised for these studies given vocally-dedicated brain nuclei and a quantifiable output (birdsong). Our prior publication reve...

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Literature Corpus work: 738b1840-8521-5f44-8dab-045cff74d88a
DOI: 10.1101/2025.09.11.675693

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