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Pan-Genomic Study of Mycobacterium tuberculosis Reflecting the Primary/Secondary Genes, Generality/Individuality, and the Interconversion Through Copy Number Variations

17 Aug 2018

Abstract excerpt

In the past two years, tuberculosis (TB) has surpassed HIV as the leading infectious disease killer worldwide. The main pathogen, Mycobacterium tuberculosis (Mtb), contains ~4000 genes that account for ~90% of the genome. However, it is still unclear which of these genes are primary/secondary, which are responsible for generality/individuality, and which interconvert during evolution. We utilized a pan-genomic...

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PMID: 30177918
DOI: 10.3389/fmicb.2018.01886

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