Article

Skp2 Stabilizes Mcl-1 and Confers Radioresistance in Colorectal Cancer

2021-07-07

Abstract excerpt

<title>Abstract</title> <p>Background Overexpression of Skp2 plays a critical role in tumorigenesis and correlates with poor prognosis in human malignancies. Thus, Skp2 has been proposed as an attractive target for anti-tumor interventions. Methods The expression of Skp2 in human colorectal cancer (CRC) and the role of Skp2 in tumorigenic properties and irradiation sensitivities of CRC cells were examined by an...

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Literature Corpus work: 7337c6f5-748d-5b9f-ac5e-95e756756a63
DOI: 10.21203/rs.3.rs-645311/v1

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