Article
SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1
2020-12-10
Abstract excerpt
<title>Abstract</title> <p><bold>Background: </bold>Cancer stem cells (CSCs) have been recognized as an important drug target, however, the underlying mechanisms have not been fully understood. SKP1 is a traditional drug target for cancer therapy, while, whether SKP1 promotes colorectal cancer (CRC) stem cells (CRC-SCs) and the underlying mechanisms have remained elusive. <bold>Methods: </bold>Human CRC cell line...
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Identifiers and source
- Literature Corpus work
- 5880294a-3026-571d-bf71-7ac89e74fa79
- DOI
- 10.21203/rs.3.rs-29004/v3