Article

Blood Interleukin-6 (IL-6) mRNA Expression in Alzheimer’s Disease: A Preliminary Analysis

2025-07-14

Abstract excerpt

<h4>Introduction</h4> Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by amyloid protein deposition, phosphorylated tau and neurodegeneration. Interleukin-6 (IL-6) is a pro-inflammatory cytokine implicated in neurodegenerative diseases (9,10). <h4>Objective</h4> This study aimed to investigate the expression level of the IL-6 probe in blood samples from the GSE63060 dataset to determine if...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 73086579-b8aa-54f9-8a8f-6ce469c91049
DOI: 10.1101/2025.07.13.25331470

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Blood Interleukin-6 (IL-6) mRNA Expression in Alzheimer’s Disease: A Preliminary AnalysisDOI 10.1101/2025.07.13.25331470Read

Cytokine expression profile in the human brain of older adultsSemantic proximity Read

Toward an Alzheimer's disease diagnosis via high‐resolution blood gene expressionSemantic proximity Read

Tracking the progression of Alzheimer’s disease with peripheral blood monocytesSemantic proximity Read

Plasma IL-6 levels and their association with brain health and dementia risk: A population-based cohort study.Semantic proximity Read

Decreased interleukin-8 levels in the peripheral blood of Alzheimer’s patientsSemantic proximity Read

Impaired type I interferon signaling activity implicated in the peripheral blood transcriptome of preclinical Alzheimer’s diseaseSemantic proximity Read

Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease.Semantic proximity Read

Association study of the BIN1 and IL-6 genes on Alzheimer's disease.Semantic proximity Read

IL-6-174 G/C and -572 C/G polymorphisms and risk of Alzheimer's disease.Semantic proximity Read

Polymorphism 174 G/C of interleukin 6 gene in Alzheimer's disease--preliminary report.Semantic proximity Read

Interleukin-6 -174G/C polymorphism and the risk of Alzheimer's disease in Caucasians: a meta-analysis.Semantic proximity Read

Interleukin-6 gene (-174 C/G ) and apolipoprotein E gene polymorphisms and the risk of Alzheimer disease in a Polish population.Semantic proximity Read