Article
Polymorphism 174 G/C of interleukin 6 gene in Alzheimer's disease--preliminary report.
Neurologia i neurochirurgia polska - 1 Jan 2000
Paradowski Bogusław, Celczyńska Dorota, Dobosz Tadeusz, Noga Leszek
Abstract excerpt
BACKGROUND AND PURPOSE: Interleukin 6 (IL-6) is one of the mediators of inflammation in the neurodegenerative process in Alzheimer's disease (AD). The aim of the study was to identify the risk of AD incidence in carriers of the polymorphism of genotype IL-6-174G/C. MATERIAL AND METHODS: The study covered 51 patients (34 women and 17 men, average age: 73.0+/-6.9 years) who met the NINCDS-ADRDA criteria of probable...
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