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The Janus face of DNA methylation in aging

3 Mar 2010

Abstract excerpt

Aging is arguably the most familiar yet least-well understood aspect of human biology. The role of epigenetics in aging and age-related diseases has gained interest given recent advances in the understanding of how epigenetic mechanisms mediate the interactions between the environment and the genetic blueprint. While current concepts generally view global deteriorations of epigenetic marks to insidiously impair...

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PMID: 20354272
DOI: 10.18632/aging.100124

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