Article

Humanized yeast to study the role of human ECE-1 isoforms in apoptosis in congenital heart disease

2023-06-19

Abstract excerpt

Endothelin convert enzyme-1(ECE-1) plays a significant role in cardiovascular development including four isoforms with unclear function. Therefore, we are interested in studying the function of ECE-1 isoforms through mitochondria due to the high correlation between congenital heart disease (CHD) and apoptosis. Since the expression of human Bax and Bcl-xL in budding yeast ( Saccharomyces cerevisiae ) results in si...

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Literature Corpus work: 72f6080e-63a6-5268-8553-2fa4879da1c0
DOI: 10.1101/2023.06.19.545519

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