Article
[The apoptosis-inducing activity of human selenoprotein P shorter isoform].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Nov 2004
Fang Qing, Yi Yao, Zheng Yan-hua, Chen Quan, Ning Li, Zha Yuan-yuan, Bi Sheng-li, Yang Jian-guo, Lin Chen
Abstract excerpt
OBJECTIVE: Human selenoprotein P (HSelP) is unique protein that contains 10 selenocysteines encoded by 10 inframe UGA, which typically function as stop codon. The function of HSelP remains unclear, in part due to the inability to express it by gene recombinant technique. This study is to investigate expression and purification of recombinant HSelP in prokaryotic expression system, and its activity to induce...
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